参考信息

参考依据（Reference Basis)

  1. 中国居民膳食指南,中国营养学会编著，人民卫生出版社，2016
  2. 营养与食品卫生学（第八版），孙长颢主编，人民卫生出版社，2017
  3. 临床营养学（第3版）. 顾景范主审，人民卫生出版社, 2016
  4. EU SCIENCE HUB： https://ec.europa.eu/jrc/en/health-knowledge-gateway/promotion-prevention/nutrition/food-based-dietary-guidelines
  5. U.S. Food and Drug Administration：https://www.fda.gov/food
  6. 营养师公会全国联合会： http://www.dietitians.org.tw/
  7. 台湾营养学会： https://www.nutrition.org.tw/index.html
  8. 卫生福利部食品药物管理署： https://consumer.fda.gov.tw/
  9. 财团法人食品工业发展研究所： https://train.firdi.org.tw/tsci/index.asp
  10. 社团法人糖尿病卫教学会： https://www.tade.org.tw/news/
  11. 台湾肾脏医学会： https://www.tsn.org.tw/
  12. 台湾运动营养学会： http://tssn.utaipei.edu.tw/
  13. 台弯保健食品学会： http://www.thfs.com.tw/

原理资讯 （Additional Information）

小慧检测仪采用王唯工教授的[气血共振原理]，该技术基于30多年的研究基础。数十年的动物研究[1-5]，实验室模拟[6-9]，数学建模[10-17]和人体临床试验[18-23]，已经建立了动脉脉搏频谱和每个主要器官动脉树上驱动力之间的相关性。当心脏泵送有限量的血液携带氧气和营养物质时，资源的分配将根据此时传感器在体内的反馈进行分类。

使用手指扫描可以在不到几分钟的时间内收集这些信息。众所周知，可以在心室-动脉系统的末端感知到动脉的径向运动，这使我们能够测量手臂，手腕和手部的血压。从心脏排出的血液的动能转换为主动脉壁的弹性势能后，动脉壁拥有大部分可转移能量，并在径向方向上进行稳定分布的欠阻尼强迫振荡[6，10， 11]。整个心室-动脉系统共同发挥作用，其整体特征反映在任何身体部位的血压中[11-13]。血压由弹性动脉壁的低耗散径向动量方程控制，该方程使脉冲甚至存在于心室-动脉系统的末端[14]。脉冲的频率分析包含与作用在特定固有频率器官上的力源相关的信息[2，5,14,17]。

我们先进的健康监测系统准确性的关键是分析所依据的严谨科学研究。自1985年以来，研究人员王唯工博士和王林玉英博士研究了脉搏波形与全身血流之间的关系。医学和生物工程学杂志，应用物理杂志和生理学杂志上的出版物构成了每次阅读所用分析的基础。

The technology is based on the foundation of more than 30 years of research. Decades of animal studies [1-5], lab simulations [6-9], mathematical modeling [10-17] and human clinical trials [18-23] have established the correlation between the arterial pulse spectrum and the driving force on the arterial tree of each major organ. When a heart pumps limited amount of blood carrying oxygen and nutrients, the distribution of the resource is triaged based on the feedback of the sensors in the body at that very moment.

This information can be collected in just under a few minutes using a finger scan. It is commonly known that the arterial radial motion can be sensed at the ends of the ventricular-arterial system and that enables us to measure the blood pressure in our arms, wrists and hands. After the kinetic energy of the blood ejected from the heart converts to the elastic potential energy of the aortic wall, the arterial wall possesses most of the transferable energy and conducts a steady distributed under-damped forced oscillation in the radial direction [6, 10, 11]. The entire ventricular-arterial system performs collectively and its overall character is reflected in the blood pressure at any of the body parts [11-13]. The blood pressure is governed by the low dissipation radial momentum equation of the elastic arterial wall which makes the pulse exists even at the ends of the ventricular-arterial system [14]. The frequency analysis of the pulse contains information correlated with the force source acting on organs of specific natural frequencies [2, 5,14,17].

The key to the accuracy of our advanced health monitoring system is the rigorous scientific research underlying the analysis. Since 1985, researchers Dr. Wei-Kung Wang and Dr. Yuh-Ying Lin Wang have studied the relationship between the pulse waveform and blood flow throughout the body. Publications in the Journal of Medical and Biological Engineering, the Journal of Applied Physics, and the Journal of Physiology, form the foundation of the analysis used for each reading.

动物研究（Animal Studies ）

  1. Wang SH, Jan MY, Wang WK, Wang YY. Effects of antihypertensive drugs on specific harmonic indices of the pulse waveform in normotensive Wistar Kyoto rats. Clin Exp Hypertens. 2012;34:74-8.
  2. Hsu TL, Chao PT, Hsiu H, Wang WK, Li SP, Wang YY. Organ-specific ligation-induced changes in harmonic components of the pulse spectrum and regional vasoconstrictor selectivity in Wistar rats. Exp Physiol. 2006;91:163-70.
  3. Hsiu H, Jan MY, Wang WK, Wang YY. Effects of whole-body mechanical stimulation at double the heart rate on the blood pressure waveform in rats. Physiol Meas. 2006;27:131-44.
  4. Hsu TL, Chao PT, Jan MY, Wang WK, Li SP, Wang YY. Effects of angiotensin II on flux rise time in rats (a time index of laser Doppler flowmetry) and its relation with microvascular structures. Microvasc Res. 2008;75:211-6.
  5. Jan M-Y, Hsiu H, Hsu T-L, Wang W-K, Wang Y-YL. The Physical Conditions of Different Organs Are Reflected Specifically in the Pressure Pulse Spectrum of the Peripheral Artery. Cardiovascular Engineering. 2003;3:21-9.

实验室模拟（Lab Simulations）

  1. Wang Y-YL, Sze W-K, Lin C-C, Chen J-M, Houng C-C, Chang C-W, et al. Examining the response pressure along a fluid-filled elastic tube to comprehend Frank’s arterial resonance model. Journal of Biomechanics. 2015.
  2. Wang YY, Wang GC, Chen YH, Guo DJ, Wang WK. The eccentric position of the heart in the mammalian body and optimal energy transfer in single tube models. Physiol Meas. 2005;26:99-108.
  3. Hsu TL, Hsiu H, Chao PT, Li SP, Wang WK, Wang YY. Three-block electrical model of renal impedance. Physiol Meas. 2005;26:387-99.
  4. Wang YY, Jan MY, Wang GC, Bau JG, Wang WK. Pressure pulse velocity is related to the longitudinal elastic properties of the artery. Physiol Meas. 2004;25:1397-403.

数学建模（Mathematical Modeling）

  1. Lin Wang YY, Wang WK. From a basic principle of evolution to the heart rate of mammals. J Physiol. 2015;593:2241-2.
  2. Lin Wang YY, Wang WK. Anatomy of arterial systems reveals that the major function of the heart is not to emit waves associated with the axial blood motion. The Journal of physiology. 2014;592:409.
  3. Wang Y-YL, Wang W-K. A hemodynamics model to study the collective behavior of the ventricular-arterial system. J Appl Phys. 2013;113:024702.
  4. Wang YYL, Hsu TL, Jan MY, Wang WK. Theory and Applications of the Harmonic Analysis of Arterial Pressure Pulse Waves. J Med Biol Eng. 2010;30:125-31.
  5. Wang YYL, Sze WK, Bau JG, Wang SH, Jan MY, Hsu TL, et al. The ventricular-arterial coupling system can be analyzed by the eigenwave modes of the whole arterial system. Appl Phys Lett. 2008;92.
  6. Wang YYL, Chiu WB, Jan MY, Bau JG, Li SP, Wang WK. Analysis of transverse wave as a propagation mode for the pressure pulse in large arteries. J Appl Phys. 2007;102.
  7. Wang YYL, Jan MY, Shyu CS, Chiang CA, Wang WK. The natural frequencies of the arterial system and their relation to the heart rate. IEEE T Bio-Med Eng. 2004;51:193-5.
  8. Wang YY, Chang SL, Wu YE, Hsu TL, Wang WK. Resonance. The missing phenomenon in hemodynamics. Circ Res. 1991;69:246-9.

人体临床试验（Human Clinical Trials）

  1. Hsiu H, Hsu CL, Chen CT, Hsu WC, Lin FC. Effects of acupuncture on the harmonic components of the radial arterial blood-pressure waveform in stroke patients. Biorheology. 2013;50:69-81
  2. Hsiu H, Hsu WC, Hsu CL, Huang SM. Assessing the effects of acupuncture by comparing needling the hegu acupoint and needling nearby nonacupoints by spectral analysis of microcirculatory laser Doppler signals. Evidence-based complementary and alternative medicine : eCAM. 2011;2011:435928.
  3. Hsu TL, Chiang Y, Wang WK, Chao PT, Bao JG, Wang YY. Pulse Analysis as a Possible Real-Time Biomarker Complementary to SGPT and SGOT for Monitoring Acute Hepatotoxicity. Toxicol Mech Methods. 2003;13:181-6.
  4. Wang WK, Tsuei J, Chang HC, Hsu TL, Wang YY. Pulse spectrum analysis of chemical factory workers with abnormal blood test. The American journal of Chinese medicine. 1996;24:199-203.
  5. Lu WA, Cheng CH, Lin Wang YY, Wang WK. Pulse spectrum analysis of hospital patients with possible liver problems. The American journal of Chinese medicine. 1996;24:315-20.
  6. Chen CY, Wang WK, Kao T, Yu BC, Chiang BC. Spectral analysis of radial pulse in patients with acute, uncomplicated myocardial infarction. Jpn Heart J. 1993;34:131-43.
  7. Wang Y-YL, Wang W-K. Why the cardiovascular studies should start with the radial oscillation of arterial wall rather than from axial flow motion of blood. International journal of cardiology 2018.
  8. Lin Wang YY, Wang WK. Did you know How the cardiovascular system achieves its high efficiency as a compound irrigation device and why this is relevant to future cardiovascular studies. Acta Physiologica 2018.
  9. Chang C-W, Liao K-M, Chen Y-C, Wang S-H, Jan M-Y, Wang G-C. Radial pulse spectrum analysis as risk markers to improve the risk stratification of silent myocardial ischemia in Type 2 diabetic patients. IEEE journal of translational engineering in health and medicine 2018.
  10. Chang C-W, Liao K-m, Chang Y-T, Wang S-H, Chen Y-c, Wang G-C. The effect of radial pulse spectrum on the risk of major adverse cardiovascular events in patients with type 2 diabetes. Journal of diabetes and its complications 2018.
  11. Chang C-W, Liao K-m, Chang Y-T, Wang S-H, Chen Y-c, Wang G-C. The First Harmonic of Radial Pulse as an Early Predictor of Silent Coronary Artery Disease and Adverse Cardiac Events in Type 2 Diabetic Patients. Cardiology research and practice 2018.

媒体报道（Media Reporting）

  1. Media American Heart Association. "Pulse waves measured at the wrist uncover often-missed artery changes in menopausal women." ScienceDaily. ScienceDaily, 29 July 2019.
  2. https://newsroom.heart.org/news/pulse-waves-measured-at-the-wrist-uncover-often-missed-artery-changes-in-menopausal-women

专利（Granted Patents）

注：此非医疗建议，仅作为保健参考用，不可视为疾病诊断、医治之用，若有身体不适应尽速就医。